UMASS Memorial Health Care Histocompatibility laboratory (HLA lab) provides comprehensive and state-of-the-art Histocompatibility and Immunogenetics testing services supporting hematopoietic stem cell transplantation (HSCT), solid organ transplantation, and platelet transfusions programs. The HLA lab also provides DNA-based HLA donor registry typing for Caitlyn Raymond International Registry. The laboratory services includes but not limited to detection and identification of HLA antibodies in sensitized patients and donors; determination of HLA types of patients and blood donors to assist in the provision of HLA-matched platelet transfusions; HLA testing to support HSCT and solid organ transplantation; circulating CD34+ cell quantification by flow cytometry; identification of disease predisposition HLA genes for Celiac disease, narcolepsy,Ankyllosing spondylitis, and others; identification of drug hypersensitivity related HLA genes, including: HLA-B* 5701 with Abacavir, HLA-B*1502 with Carbamazepine, HLA-B*5801 with Allopurinol, etc.

The HLA lab is located at 119 Belmont St., Worcester, MA with newly renovated space and a team of dedicated staff led by Neng Yu, MD, dip ABHI, who joined UMASS in 2006. Dr. Yu has worked in the field of Histocompatibility and Immunogenetics since 1990 and is experienced in all aspects of HLA testing. UMASS Memorial Health Care Histocompatibility laboratory is CLIA-certified and accredited by agencies including the American Society for Histocompatibility and Immunogenetics (ASHI), the College of American Pathologists (CAP) and the United Network for Organ Sharing (UNOS).

STAT testing service is available, contact the laboratory for details.

Operation Hours
The laboratory operates Monday through Friday from 6:30 am to 8:00 pm.

UMass Memorial Medical Center, Clinical Laboratories
365 Plantation Street
Worcester, MA 01605
Phone: 508-334-6892
Fax: 508-334-6846